Immune System & Autoimmunity
"T-Reg Cell Function, Secretory IgA & Chronic Inflammation"
A resilient immune system requires precise balance between pathogen defense and self-tolerance. Autoimmunity occurs when T-regulatory cell balance breaks down.
From Lisa Cutforth — Clinical Nutritionist
"Autoimmunity is not an aggressive immune system to be suppressed, but a confused immune system to be re-educated with vitamin D, gut barrier repair, and inflammation control."
Lisa Cutforth
BSc. Hons. (Nutrition & Psychology) · Walsh Protocol Practitioner
Cellular Pathways
Biochemical Mechanism & Systems Interplay
The body does not operate in silos. Here is the biochemical reality of how nutrient cofactors govern immune system & autoimmunity.
Vitamin D receptor (VDR) activation upregulates FoxP3 expressing T-regulatory cells, which prevent autoimmune attacks. Secretory IgA (sIgA) serves as the first-line mucosal barrier defense.
"When we correct enzymatic blocks with bio-available cofactors, physiology realigns naturally."
Standard blood ranges are designed to detect acute disease. We look for optimal functional biochemistry.
- Vitamin D3 (25-OH) & 1,25-Dihydroxy Vitamin D Ratio
- Secretory IgA (sIgA)
- Autoantibody Panels (ANA, Thyroid Antibodies)
- hs-CRP & ESR
Therapeutic Nutrition
Where Nutrition Enters Immunity & Autoimmune
Nutrients act as chemical keys for the enzymatic locks controlling your physiological state.
Vitamin D3 with K2 & Vitamin A
Prescribed based on strict individual biochemistry, therapeutic dosing windows, and cofactor synergy.
Zinc & Vitamin C
Prescribed based on strict individual biochemistry, therapeutic dosing windows, and cofactor synergy.
Quercetin & Resveratrol
Prescribed based on strict individual biochemistry, therapeutic dosing windows, and cofactor synergy.
Probiotic Strains for sIgA Production
Prescribed based on strict individual biochemistry, therapeutic dosing windows, and cofactor synergy.
Expert Understanding
Frequently Asked Clinical Questions
Explore The Web
Connected Health Pillars
Women's Health & Hormones
Hormone synthesis, follicle maturation, and endometrial cycling require precise nutritional inputs across all 28 days. From heavy menstrual bleeding to perimenopausal transition, targeted nutrition balances oestrogen detoxification, luteal progesterone support, and thyroid interactions.
Gut-Brain Axis & Microbiome
Over 90% of the body's serotonin and a significant portion of GABA are generated in the gastrointestinal tract. Intestinal dysbiosis and leaky gut directly trigger neuroinflammation through bacterial lipopolysaccharides (LPS).
Adrenal & Stress Physiology
Chronic stress alters the hypothalamic-pituitary-adrenal (HPA) axis, depleting vital cofactors required for cortisol synthesis, catecholamine regulation, and thyroid activation.
Restore Your Biology with Precision
Ready to resolve your symptoms at the genetic and biochemical root? Lisa Cutforth provides bespoke, confidential consultations in Brisbane and via Telehealth Australia-wide.